Explains the medication hydrocodone/ acetaminophen (Vicodin, Vicodin ES, Vicodin HP, Anexsia, Lortab, Lorcet, Lorcet Plus, Norco, Zydone) a narcotic drug used as a pain reliever and cough suppressant. Article includes descriptions, uses, drug interactions, and side effects. Read more about the prescription drug hydrocodone/ acetaminophen. When looking at Lortab vs. Norco, they are very similar. One of the primary differences you’ll see is the amount and ratio they have of hydrocodone to acetaminophen. My Dr. changed my prescription from Lorcet to Norco because Norco has less Acetaminophen in it. He is concerned because of my liver (another story for another day). Norco is the brand name for a prescription medication that combines hydrocodone, an opioid (narcotic) pain reliever with acetaminophen. As you probably know, acetaminophen is an over-the-counter (OTC) non-opioid pain reliever. Subutex (Buprenorphine), was approved for treatment of opioid addiction. However, as an opioid drug it can lead to abuse and addiction. -Your doctor is switching you from Lortab 10s (which is not regular dose) to Norco 10s is what you are saying. As you are already aware, the Lortab 10/500 is 10mg of hydrocodiene and 500mgs of acetaminophen and you can read the Norco 10/325 the same way. Opioids have taken center stage in the U.S. in recent years, and not in a positive way. The level of abuse of prescription opioids has risen dramatically in the past 15 years, and among two of the biggest culprits for this abuse are oxycodone and hydrocodone. You are wrong. Perks are usually percribed with Ty in it. But you can also get Perks without the Ty in it too. I take 5mg Perks/325 Ty. So to say Perks only have Oxycodone in it no Ty has no idea what they are talking about. More on how modes of administration affect hydrocodone onset here. Hydrocodone - Wikipedia, the free encyclopedia Hydrocodone is a semi-synthetic opioid synthesized from codeine, one of the opioid alkaloids. Hydrocodone, the active ingredient in drugs like Norco and Vicodin, and oxycodone, the active ingredient in Percocet and OxyContin, are two of the most popular opioid — or narcotic — analgesics prescribed for pain relief.